Zoladex 3.6mg Depot Safesystem 3.6mg Syringe POM x1

Zoladex 3.6mg implant SafeSystem 1 pre-filled syringe

Therapeutic Indications:

1. Prostate Cancer Treatment:

• Metastatic prostate cancer:

Has demonstrated comparable survival benefits to surgical castrations.

• Locally advanced prostate cancer (alternative to surgical castration):

Has demonstrated comparable survival benefits to anti-androgen therapy.

• Adjuvant treatment to radiotherapy:

For patients with high-risk localised or locally advanced prostate cancer, Zoladex has demonstrated improved disease-free survival and overall survival.

• Neo-adjuvant treatment prior to radiotherapy:

In high-risk localised or locally advanced prostate cancer, Zoladex has demonstrated improved disease-free survival.

• Adjuvant treatment to radical prostatectomy:

For patients with locally advanced prostate cancer at high risk of disease progression, Zoladex has demonstrated improved disease-free survival.

2. Advanced Breast Cancer:

For pre and perimenopausal women suitable for hormonal manipulation.

3. Early Breast Cancer (Zoladex 3.6 mg):

An alternative to chemotherapy in the standard of care for pre/perimenopausal women with oestrogen receptor (ER) positive early breast cancer.

4. Endometriosis:

Zoladex alleviates symptoms, including pain, and reduces the size and number of endometrial lesions.

5. Endometrial Thinning:

This is for thinning the uterine endometrium prior to endometrial ablation or resection.

6. Uterine Fibroids:

In conjunction with iron therapy, Zoladex helps in the haematological improvement of anaemic patients with fibroids prior to surgery.

7. Assisted Reproduction:

Used for pituitary downregulation in preparation for superovulation.

Nature and Contents of Container:

• Single dose Safe System™ syringe applicator with a protective sleeve.

Special Precautions for Storage:

• Do not store above 25°C.